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nonlinear curve-fitting program graphpad prism 8  (GraphPad Software Inc)


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    GraphPad Software Inc nonlinear curve-fitting program graphpad prism 8
    Nonlinear Curve Fitting Program Graphpad Prism 8, supplied by GraphPad Software Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/curve+fitting+program+graphpad+prism/prism+curve+fitting+software/bio_rxiv__2025__01__29__635371-173-7-9
    Average 90 stars, based on 1 article reviews
    nonlinear curve-fitting program graphpad prism 8 - by Bioz Stars, 2026-09
    90/100 stars

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    Related Articles

    Binding Assay:

    Article Title: α₁-Adrenoceptor and serotonin 5-HT(1A) receptor affinity of homobivalent 4-aminoquinoline compounds: an investigation of the effect of linker length.
    Article Snippet: a1-adrenoceptor (a1-AR) subtype-selective ligands lacking off-target affinity for the 5-HT1A receptor (5HT1A-R) will provide therapeutic benefits in the treatment of urogenital conditions such as benign prostatic hyperplasia.. In this study we determined the affinity of 4-aminoquinoline and eleven homobivalent 4-aminoquinoline ligands (diquinolines) with alkane linkers of 2–12 atoms (C2–C12) for a1A, a1B and a1D -ARs and the 5-HT1A-R.. These ligands are a1A-AR antagonists with nanomolar affinity for a1A and a1B -ARs.

    Article Title: 5-HT1A receptor pharmacophores to screen for off-target activity of α1-adrenoceptor antagonists.
    Article Snippet: The a1-adrenoceptors (a1-ARs), in particular the a1A-AR subtype, are current therapeutic targets of choice for the treatment of urogenital conditions, such as benign prostatic hyperplasia (BPH).. Due to the similarity between the transmembrane domains of the a1-AR subtypes, and the serotonin receptor subtype 1A (5-HT1A-R), currently used a1-AR subtype-selective drugs to treat BPH display considerable off-target affinity for the 5-HT1A-R, leading to side effects.. We describe the construction and validation of pharmacophores for 5-HT1A-R agonists and antagonists.

    Article Title: Ir-LBP, an Ixodes ricinus Tick Salivary LTB4-Binding Lipocalin, Interferes with Host Neutrophil Function
    Article Snippet: .. Saturation experiments were analyzed by non-linear regression using the curve fitting program GraphPad Prism® (GraphPad software, San Diego, CA, U.S.A.), B = (Bmax [F])/KD+[F]), where B is the amount of bound ligand at equilibrium, Bmax is the maximum number of binding sites, [F] is the concentration of free ligand and KD is the ligand dissociation constant. ..

    other:

    Article Title: Effects of formoterol and salmeterol on cytokine release from monocyte-derived macrophages.
    Article Snippet: Concentrationresponse curves were analysed by least-squares, non-linear iterative regression using the ‘‘GraphPad Prism’’ curve fitting program (GraphPad software, San Diego, CA, USA) and mean effective concentration (EC50) values were subsequently interpolated from curves of best-fit.

    Article Title: Molecular characterization of c-Abl/c-Src kinase inhibitors targeted against murine tumour progenitor cells that express stem cell markers.
    Article Snippet: Curve fitting was performed with the program GraphPad Prism.

    Article Title: Dichloroacetate and PX-478 exhibit strong synergistic effects in a various number of cancer cell lines
    Article Snippet: The EC 50 values were calculated via curve fitting with the program GraphPad Prism.

    Concentration Assay:

    Article Title: Ir-LBP, an Ixodes ricinus Tick Salivary LTB4-Binding Lipocalin, Interferes with Host Neutrophil Function
    Article Snippet: .. Saturation experiments were analyzed by non-linear regression using the curve fitting program GraphPad Prism® (GraphPad software, San Diego, CA, U.S.A.), B = (Bmax [F])/KD+[F]), where B is the amount of bound ligand at equilibrium, Bmax is the maximum number of binding sites, [F] is the concentration of free ligand and KD is the ligand dissociation constant. ..



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